let's call you
What is infertility?
- We request couples to apply to an expert center in the event that pregnancy does not occur although they have regular sexual intercourse three times a week in average within a year. This situation is examined under the title of infertility. The pregnancy rate of a healthy couple is about 20% per menstrual cycle. Regarding this information, the possibility of pregnancy is over 80-90% in a year. If there is a disease knwon or wife’s age is over 35 within this one year, the couples should apply earlier.
What are the assisted reproductive techniques?
- Apart from the simple trackings such as the following of the egg developing within the menstrual cycle every month with the ultrasound, detection of ovulation and intimacy recommendation in proper period, vaccination in the event of problems about sexual intercourse, rareness of sperm amount or existence of unexplainable infertility; application of in vitro fertilization and intracytoplasmic sperm injection “ICSI” in the event of more negative conditions or failures in obtaining pregnancy as a result of 2 vaccinations; the methods such as the assisted budding and preimplantation genetic diagnosis are included under the assisted reproductive techniques frequently used.
Do life styles and feeding habits have any effect on infertility?
Dangerous foods which may have affect the infertility can be ranked as alcohol, cigarette and similar agents. Smoking and alcohol cause especially ovary aging because of their toxic effects and they cause menopause and repeating IVF failures. The vitamine A derivative retinoic acid of high dose used in acne treatment is known for having negative effects on the ovary functions. For healthy ovary function, it is recommended to plan the food received as suitable to general life rules, stay away from radiation and freeze the eggs for future before using the chemotherapeutic drugs. Protection the testicles from overheat in men is important in terms of fertility.
Is infertility treatment hard?
The duration and hardness of the infertility treatment change according to the reason of the infertility. Infertility duration, existence of companying man and woman factors, previous trials and their results, woman’s age are important factors which determine the treatment process and style.
What should be done and when should couples apply for a treatment if pregnancy does not occur although there is not any medical problem and they have regular sexual intercourse?
As indicated in the definition, if pregnancy does not occur in the event of regular sexual intercourse for a year, young couples can be evaluated in terms of infertility. However, especially women of 35th age and above should apply to infertility clinics earlier because of the possible situations such as ovary aging and early menopause. Having ovary surgery story, existence of early menopause in family, radiotherapy or chemotherapy story are among the reasons which make the patient come to the clinic earlier. In this meeting, couples are examined separately and evaluation of gynecological and men factors is made. Treatment steps such as spermiogram test to research the men factor, ultrasound control because of women factor, radiological investigation of the tubes and hormonal evaluation are followed.
How long should patients of old age wait?
Consultancy in patients who are over 35th age and want a child can be performed at the earliest. Likewise, the patients who have a story of surgery that reduces the ovary reserve, chocolate cyst, radiotherapy or chemotherapy although they are young can be investigated earlier. In healthy individuals, it is proper to follow them for 1 year and investigate in terms of infertility when pregnancy does not occur at the end of this period
What is vaccination?
It is the process that after wife’s ovulation is increased with drugs used orally or with injection and followed, cracking injection is applied to obtain a mature egg and sperms which are man germcells are taken with masturbation or similar alternative methods about 32-36 hours later after this injection, and then after the man genital system is cleared of special secretions and concentrated and “washed“, it is given into the “womb“, woman genital system, with the help of a catheter. It is an easy and painless application.
How many times can vaccination be applied?
- It can be tried three times after the drug usage and egg development according to patient’s age and infertility reason. It will be the right option to try IVF treatment when vaccination is unsuccessful because the following trials do not increase the possibility of pregnancy.
Is vaccination proper for every infertility couple?
It is necessary not to recommend vaccination treatment in the event of patients with the story of severe men factor infertility (if the total mobile sperm amount is below 10 million) or situations in which woman tubes are blocked.
What is tube baby treatment?
It is the process of increasing the ovulation in woman with the drugs used, application of aging injection after being convinced that the eggs are mature enough and collection of these eggs with the ultrasound under anaesthesia, and fertilization of both sexes’ cells in laboratory conditions by sampling the man gamets taken from the husband and transfer of the embryos created into the woman genital system.
What does unmedicated tube baby (In Vitro Maturation) mean?
In this method, egg cells obtained from wife without using any drugs or by using some drug for a short period without waiting for them to be mature and sperms taken from husband are processed in the laboratory conditions and embryos are transferred into the woman genital system.
How is private tube baby treatment?
It is necessaru to evaluate and investigate female and male individuals before the treatment. Situations such as tubal pathologies, ovary cysts, endometrial polypes, myomas, bleeding irregularity, lowness of ovary reserve available in woman should be investigated one by one and prepared for the treatment. Likewise, evaluation of male individiual and consultancy of him by urology unit in necessary situations constitute the base of the treatment. Under these conditions, laparoscopy or hysteroscopy surgery is sometimes recommended for women patients according to the pathology available before the tube baby treatment. Another iimportant issue is that while determination of the medicine treatment according to the ovary reserve detected ensures the best answer for the patient, it also increases the pregnancy rates. Evaluating the couples in the best way and planning a treatment special for them is very crucial.
Whom is tube baby treatment applied?
Tube baby treatment can be applied on every patient who wants to have a child but cannot get pregnant in natural ways in the event of existence of woman and man eggs.
If there is myoma or cyst in the ovary, is tube baby treatment applied?
Myomas which fill the endometrial cavity or press the cavity may prevent embryos to be implanted. Likewise, ovary cysts may prevent the follicule growing during the medical treatment. For this reason, it can be considered to remove myomas or receive ovary cysts if necessary before the treatment. Thus, the question that which myoma and ovary cysts should we deal with before the treatment is a decision that can be made only after examining the patient.
Is tube baby treatment applied when there is endometriosis or endometrioma “chocolate cyst”?
Endometriosis is a serious disease that may cause infertility. It may cause adherence in tubes and decrease in ovary reserve. The treatment can be planned according to the seriousness and stage of the disease. Sometimes steps like removing the ovary cysts (chocolate cyst) and opening the adherences within the stomach may increase the pregnancy rates. Yet, it is not necessary to remove all of them, because tube baby treatment can also be planned while these chocolate cysts exist. The removing operation of these cysts should be made as laparoscopic and surgery is important because there is a risk of decrease in ovary reserve.
Is it possible to have a child with the tube baby treatment after cancer?
After the treatment of diseases like cancer, the ovary reserve or sperm production may be affected negatively in different ways according to the disease type and treatment kind used, so before beginning such treatments, it is recommended to freeze reproductive cells. If the patient wants to have a child after he/she wants to have a child, infertility treatment can be applied.
Does age have any effect on the application of tube baby?
The pregnancy rates may decrease in patients with old age. Factors such as lowness of egg amount obtained after IVF treatment and increase in the risk of abortion may cause failures
How long does tube baby treatment take?
In IVF treatment, menstrual cycle is tried to be imitated. For this reason, the treatment lasts for 9-12 days in average. Sometimes this period can be lengthened in precursor treatments and can be 25-27 days. After the eggs are collected, embryos are transferred 2-6 days later. After about 11-12 days, the result of pregnancy test is looked. In other words, the result is obtained within 1 month after the beginning of the treatment. The first 9-12 days of this period pass under clinic observation.
What does the price packet of tube baby treatment include?
In pre-interviews, no price is applied in our center. USG tracking, egg collecting, embryo transfer, anaesthesia package, hospital room services are not included in the price packet of the tube baby treatment. Laboratory services are reduced for these patients and childbearings of the patients who get pregnant in our clinic are performed at half price
Can sex be determined in tube baby treatment?
The sex determination of the embryo can be made with the examination of chromosomes by applying preimplantation genetic diagnosis during the treatment. However, because this is not ethical and legally forbidden, it can be applied only in a genetic necessity.
Is it necessary to stay in hospital along the treatment?
Unless the rare complications such as excessive reaction of the ovaries occur along the treatment, hospitalization is not applied. Outpatient observations which do not exceed 2 hours are made during the collection of follicules and transfer of the embryos.
How is high FSH evaluated?
FSH is one of the hormonal tests which show ovary reserve. When the ovary functions begin to decrease or a person gets older, blood level increases. High values point out a possible future fertility problem. Basal values should be evaluated with the blood estradiol level on the 2nd or 3rd day of the menstruation. Yet, AMH measurement that is one of the ovary reserve tests which are more sensitive and antral follicule amount detection are used more frequently in our center.
Is it proper to use birth control pill before the tube baby treatment?
Birth control pills are used within the frame of IVF treatment in order to increase the follicule level, to synchronize the follicule development and prevent early ovulation. Sometimes it is given also in the existence of ovary cyst.
Is sexual intercourse possible after starting the tube baby treatment application?
When there is not any situation that requires a limitation by the doctor, intercourse is not an obstacle. However, a regimen for 2 days at least is necessary prior to giving sperm sample.
How is treatment protocol to be selected in tube baby treatment determined?
If the treatment protocol is available, it changes according to the results of previous trials, age of the patient, ovary reserce and companying gynecopathology status. Protocols are chosen by the doctors.
How are injection drugs to be used in tube baby treatment applied? Can expectant mother do it by herself?
Most of the drugs are applied under the skin by the patient during the treatment. Drugs which require special application are given by the health officers with receipt in convenient times. The application of the drugs is explained for you by our center nurses in video section of our web site.
What are the steps of tube baby treatment?
Treatment steps begin with the general evaluation and continue as follicule tracking and egg collection. The eggs are processed in the laboratory environment and fertilized eggs and embryos are transferred into the mother’s womb in a certain day.
What does ovulation induction mean?
Using drugs which increase the follicule amount developing in the menstrual cycle in convenient patients and obtaining many eggs are called as ovulation induction.
What does ovulation tracking mean?
It is the application of ultrasonography at certain intervals from the first days of the menstruation within the menstrual cycle and tracking of developing follicules every other day and tracking of blood estrogen levels and recommendation of sexual intercourse or vaccination by applying or without applying the cracking injection.
What is ovulation stimulation process? What are the stages of it?
Ovulation stimuation is investigation of their development by application of drugs as oral tablets or hormonal drugs under skin. The stimulated eggs are followed by doing ultrasonography at certain intervals and looking at the estrogen level in the blood. The average period for induction is 9-12 days.
What kind of a process is the egg collection (OPU)?
It is the process of aspiration of eggs among the egg follicules developed in your ovaries with the treatment option proper for you. There is only one egg cell in each egg follicule. This is made from vagina under the guidance of ultrasonography.
Is the egg collection process (OPU) painful? How long does it take?
The eggs are collected with the help of a special injection by using ultrasound from vagina under a light anaesthesia, which is called as sedation. Due to the anaesthesia, patients do not feel any pain during the process. Light stomachaches may occur later.
The process lasts for 15-20 minutes in average. About 3 hours should be spared for this process regarding the preparation before the process and resting period after the process.
There may be sleepiness and pain in abdomen after the process with the effect of anaesthetic drugs.
What is ovary reserve?
There are egg cells between one and two million which have ability to be only one mature egg in both ovaries during childbearing in every woman. The egg cells between one and two million which have ability to be only one mature egg in the ovaries are called as ovary reserve. The number of these cells decreases to 250-400 thousands when the individual comes to ages in which the first menstruation occurs. In each menstrual cycle after this, the number of these reserve cells decreases and are consumed almost completely which causes menopause. When women come to 37-38th age, the consumption of these egg cells speeds and woman enter the menopause about ten years later. However, the number of these cells may be consumed faster in some women because of familial liability and genetic reasons and there occurs the risk of early menopause before the age of 40, so it is necessary to pay attention to this.
What is the mostly seen reason of decrease in the ovary reserve?
The number of ovary reserve cells is determined with the familial liability. For this reason, the pregnancy chances of women whose mother or sister enters the menopause in early ages (before 40) begins to decrease after the age of 30. Normally this loss in ovary reserve of women speeds after the age of 37 and results in menopause about 10-12 years later. However, this period may start earlier in some and result in early menopause before the age of 40.
Do the follicules seen during the egg collection contain only one egg?
There is only one egg cell within each egg follicule
How are sperms taken?
The sample that is necessary for semen analysis is taken into disposable sterile plastic cases with the masturbation method in our center after a sexual abstinence for 2-5 days. For men who do not have sperm in their semen, it is necessary to search sperms from the testicle through operation and take them if found (TESA or microscopic TESE process).
Can sperm sample be brought from home or somewhere else?
Sperm samples which will be brought from home or somewhere else should be in body temperature and brought to the laboratory within 1 hour. The right one is to take them in private rooms of giving sperm in the centers.
Can the number of sperms of husband be raised?
Mobility or aliveness; 50 of the every 100 sperms (50%) should move. The existence of less mobile sperm is asthenoazoospermia. Apart from the other reasons, varicosele and immunological reasons are especially responsible. If all of the cells are stable, it may be an indication of a syndrome with sometimes respiratory tract diseases.
What should be done if sperms are stable?
In the event of total stable sperms caused by no reasons, the only option is to apply ICSI (Intracytoplasmic sperm injection). Sometimes there may be mobile sperm within the tissue piece taken from the testicles. Before applying ICSI (Intracytoplasmic sperm injection), whethere these cells are alive or dead should be investigated with special tests.
What is done in the event that sperm amount is very scarce or there is no sperm as a result of spermiogram?
This situation is defined as azoospermia. After firstly being sure about the accuracy of this diagnosis, the remediable reasons which may cause this situation should be removed. If sperm number is very low after the spermiogram, microinjection is applied. In the event of lact of sperm in the semen, “TESE”, in other words searching sperm within the testicle with surgery, is necessary.
Is there any problem with the pregnancies created with the sperms obtained by biopsy from the husband?
There is no evidence about the possibility of additional problems other than the ones which may occur in normal pregnancies for pregnancies which are obtained by using sperms in this way or frozen-resolved sperms.
Can sperm be obtained from stem cell?
No. Studies continue.
What is microinjection type tube baby method?
In tube baby method, a sperm is taken and injected into the egg without waiting for fertilization of the egg and expected to become an embryo in this way. A single sperm is pulled into a special pipette by using a special microscope system and placed into a single egg and fertilization is achieved. This method is named as Microinjection (ICSI) method. The degree of the problem in sperms here does not prevent the fertilization ability. After the fertilization is achieved, the embryos obtained are transferred into semen bed and the patient is enabled to benefit from normal success rates of the tube baby..
What is the difference of microinjection from tube baby method?
ICSI (Microinjection) method is an assisted technique which helps fertilization in the tube baby method and should not be conceived as a method different from tube baby.
How is sperm which will be injected chosen in microinjection?
The mobile sperm which is the most quality is chosen regarding the mobility of sperm and morphological features and injected.
Is each egg fertilized?
The eggs should be mature and structurally normal in order to be fertilized. Only expert embryologists can make this differentiation between the eggs. In addition, a healthy embryo may not be obtained from every egg after the fertilization.
What should be done for persons without fertilization?
There is no test to be applied in order to understand why fertilization does not occur in these persons, but fertilization chance can be increased by using some special agents which increase the fertilization abilities of the eggs.
In which situations can blastocyst transfer be applied? What are the advantages and disadvantages of this process?
The last development stage of the fertilized eggs before clinging to mother’s womb is the blastocyst stage. In tube baby treatments, the most quality embryos are generally chosen and transferred on the 3rd day of the embryonal development. The blastocyst cells can be obtained by prolonging the culture durations of the embryos up to 5th or 6th day. The blastocyst cells are distinguished cells because their possibility of clinging to the womb and it is enough to transfer onlt 1 or 2 embryos from these cells, so that the risk of multiple pregnancy is practically decreased. The blastocyst transfer generally provides advantage for patients who develop many embryos. The blastocyst transfer is not recommended for patients who develop less eggs and embryos. The blastocyst transfer generally increases the pregnancy rate. In addition, the pregnancy chance is low with the embryos which do not enter the blastocyst stage.
Is a selection of healthy embryo possible?
Selection of healthy embryo is possible. Whether embryos are quality or not is determined by the expert embryologists by using special techniques and examination methods.
Whom is the genetic examination in embryos recommended to?
The preimplantation genetic diagnosis of about 50 genetic diseases is possible and genetic examination in embryos can be applied for families who have a high risk of any of these diseases.
What can be done to increase embryo quality?
The number and quality of developing embryos depend on many factors. In the first place, the number and quality of the eggs collected from the patient affect the embryo. This is the main reason of having better pregnancy results in young patients. As the individual gets older, the number and quality of the eggs collected decrease. Existence of chromosome disorder in the eggs affects negatively the embryo development. As the individual gets older, the risk of existence of chromosome disorder in embryos increases. The technical equipment of tube baby laboratory, media and liquids used, conditions of laboratory and incubators, hygienic conditions, embryologist working in the laboratory and knowledge and experiences of biologists.
How are embryos placed into the womb after the eggs are fertilized?
Transfer of the embryo into the womb is a simple process. It is placed into the womb with the help of a thin plastic catheter from womb entry in company with the ultrasound.
How many embryos should be transferred?
The number of embryos transferred is determined by the woman’s age, embryo quality and the number of trials. Because of the laws which restrict the embryo amount in Turkey, 2 embryo transfer can be made at most.
Does transfer of one embryo decrease the success chance?
The success chance with only one embryo transfer is lower in a certain group of patients when compared to the transfer of embryos more than one.
How is the time for the transfer determined?
The time for the transfer is determined by regarding the criteria such as the woman’s age, why the treatment is applied, results of the previous tube baby treatments, emrbyo quality and development features, whether preimplantation genetic diagnosis will be applied or not, the number of developing embryos and daily development speed of embryo.
How long should one rest and what should be done after the transfer?
The patient can go to his/her house 1-2 hours later after the transfer. There is no evidence that longer resting increases the pregnancy rates. House resting for the first 24 hours is sufficient, but it is recommended to avoid heavy physical activities and sexual intercourse until the test results.
Is using drugs continued after the transfer? What are the tests necessary?
In order to maintain pregnancy, vaginal gel or injection which contains progsterone and estrogen paper tape are recommended to the patient. Sometimes blood thinner injections are advised. The final diagnosis is established with the beta-HCG hormone 11 days later after the embryo transfer. After 2 weeks, pregnancy sac and baby should be seen within the womb with ultrasonography.
After the transfer, there may occur light discharge and light bleeding for 1-2 days. If the patient has difficulty in breathing, excessive abdominal swelling, excessive nausea, vomiting and fever, he/she should warn the doctor and be taken to the hospital by the doctor.When can the couples have sexual intercourse after the embryo transfer?
The patient can go to his/her house 1-2 hours later after the transfer. There is no evidence that longer resting increases the pregnancy rates. House resting for the first 24 hours is sufficient, but it is recommended to avoid heavy physical activities and sexual intercourse until the test results.
When can the individual turn to daily life or work after the transfer?
The patient can go to his/her house 1-2 hours later after the transfer. There is no evidence that longer resting increases the pregnancy rates. House resting for the first 24 hours is sufficient.
Is there any remaining embryo after the transfer? If yes, how are these stored?
As a result of obtaining good quality embryos more than the necessary amount for the transfer, remaining embryos can be stored. In the event of existence of 3-4 embryos at least in the same quality with the embryos transferred, freezing is applied. The embryos which are made durable for freezing process with the help of various chemicalls are stored within the liquid nitrogen (-196oC) after being frozen in special devices. When these embryos are required to be used again in future, they are resolved with the help of special chemicals and embryos developing are transferred into the mother’s womb.
What is donation?
The egg donation is to obtain egg cell from the women who have not infertility problem as in traditional tube baby treatments and use these eggs for another woman. After the eggs obtained from the giver woman are fertilized with the sperms of husband of the receiver woman, they are transferred into the womb of the receiver woman.
Sperm donation is applied for the situations in which no sperm is detected in man and sperm cannot be obtained from the testicles or a pregnancy which will be obtained with man’s sperm is not recommended in medical aspect. Such situations may be innate or may be seen because of some problems occurring later. This application is forbidden in our country.What is egg freezing?
A woman who stores her eggs with the method of egg freezing can catch the opportunity to have a child whenever she feels ready, even in her 50s. For this, woman is firstly enabled to produce many eggs with the help of drugs which stimulate the ovaries and are used in tube baby treatment. After the collection, the eggs are cleaned of the cells around them and normal mature eggs are stored within liquid nitrogen (-196°C) by being frozen with the fast freezing technique. The selection of the method to be used during freezing of the sensitive eggs is very important. While eggs remain alive in the rate of 60% in the first years when slow freezing method was applied, this rate has reached up to 90s% with the fast freezing method (vitrification) developed in McGill University in Montreal.
What is sperm freezing?
Sperm cells can be stored for long years as frozen and be used in assisted reproductive techniques by being resolved in any time. Storing the sperm as frozen is called as cryopreservation. The purpose here is to store an alive cell or tissue in very low temperature with minimum damage and without function loss for a long time.
What is embryo freezing and when is it frozen?
If there are embryos in sufficient number and quality, embryos are frozen with the approval of the couple participating the application. It is possible to store embryos as frozen on the 3rd or 5th day. The freezing and resolving embryos are the processes of freezing the embryos after being balanced with the chemical agents (cryoprotectant) and storing them within the liquid nitrogen of -196 centigrade degree and taking them into special culture environments in order to make them develop by keeping away from the cryoprotectant environment after being solved. Both processes should be performed carefully. In order to protect cell structure, the cells should lose water in slow velocity and be frozen with the slow cooling method. The pure water within the medium solidifies during freezing and becomes more intense than the cell. However, when small masses are cooled with the slow cooling system, there occurs excessive cooling this time and ice crystals occur although solution is frozen under the freezing temperature. If this process occurs suddenly, embryos get damaged. In order to avoid damaging, ice crystals are created very slowly with a technique called as seeding.
How long can frozen embryos be stored?
The embryos frozen by receiving licence from the couples can be stored up to 5 years in accordance with the approval of couples by making them sign permit and prolonge documents every year. The couples who want them to be stored more than 5 years should receive licence from the Health Ministry. The embryos frozen can be stored for years in accordance with the request of the couples.
What is the success chance in frozen embryos?
While good quality embryos protect their aliveness in the rates of 75-90% after freezing and resolving processes, the living chances of bad quality embryos decrease to 20-25%. The pregnancy rates change between 20-50% after the freezing and resolving processes depending upon the applied clinic and laboratory procedures, the patient’s age, infertility reason, the aliveness rate per embryo resolved.
How are the pregnancy results obtained from the frozen embryos?
The process of embryo freezing and resolving is a process completely based on the technical structure of laboratory and experience and skills of the embryologists
Is there any difference in terms of anomaly risk between normal tube baby and babies born with the frozen embryo method?
No difference has been identified between normal tube baby and babies born with the frozen embryo method so far.
Is there any difference between babies born with tube baby method and babies born in normal way?
Any meaningful difference between babies of the patients who get pregnant in normal way and babies of patients who get pregnant in tube baby method has not been recorded. These babies grow completely healthily as other babies.
Is the tracking of pregnancy occurring with tube baby different from the pregnancy in normal way?
Normal pregnancy tracking and tracking of the pregnancy obtained with tube baby are same.
Are blastocyst transfer and sole embryo transfer alternative to embryo reduction process?
The general purpose should not be only getting pregnant, but having a healthy pregnancy process for a good result. Multiple pregnancies sometimes progress with problems. The general approach in the world today is to help the patient with monomer pregnancy in accordance with the human physiology. However, when many embryos are placed in order to increase the pregnancy chance of the patient, the possibility of multiple pregnancy will increse. A healthy pregnancy and bearing are recommended with the 1 embryo transfer or sole blastocyst transfer in convenient patients. In this way, the risks of multiple pregnancy are decreased and reduction process is avoided.
What can be done if multiple pregnancy occurs?
When the reduction process is explained to family and accepted, it is applied in company with transvaginal or transabdominal ultrasound between 8-12 weeks. The total pregnancy loss from embryo reduction has been defined as 5%. If multiple pregnancy is triplet, it can be reduced to 2 by choosing one of the gestational sacs with local anaesthesia and committee report is needed for this.
Does embryo reduction process affect the pregnancy? What are the risks?
There is a risk of abortion in 5 of the 100 patients upon the beginning of bleeding, infection or pain after this process. The abortion risk continues within the 2 weeks after the embryo reducing process, but if it is overcome, the pregnancy generally continues without any problem.
Can the tube baby application result in extrauterine pregnancy?
The embryos transferred into the womb by being taken from the laboratory may place into the tubes, abdomen or womb entry in 2 of the 100 patients although the reason cannot be completely explained. In these situations, tubal pregnancy (pregnancy in tube), abdominal pregnancy (pregnancy in abdomen), cervical pregnancy (pregnancy in womb entry) are mentioned. Because these pregnancies are not within normal womb, they are called as extrauterine pregnancy.
Does the ovary reserve deplete as a result of the tube baby treatment?
In a normal menstrual cycle, egg anlages in certain amount are prepared every month and one of them will be the egg thrown and the others will be destroyed. The purpose in tube baby treatment is to mature all egg anlages prepared and obtain egg from all of them. In other words, because eggs are obtained from the egg anlages, this situation does not have any reducing effect on ovary reserve.
Do the drugs used in tube baby treatment have any side effect? Does it increase the cancer risk?
Unless used unconsciously or hearing from a circle of friends or virtual environment, drugs, gel or injections used in the tube baby treatment are used for the purpose and there is no damage detected. Follicule stimulating hormones have been used for 25-30 years in the tube baby treatment. It has never been proved that these drugs cause cancer around the world up to today.
What kind of problems may occur during the tube baby treatment and are there any risks?
– Severe allergic reaction against the sedative/painkiller drugs used during the transfer and OPU processes may occur.
– There may occur injuries in intraabdominal vessels, organs and bowels during the OPU process. Such situations may require intensive care and create a life-threatening situation.
– Skin and soft tissues may be damaged after the injections.
– The situation that is defined as ovarian hyperstimulation syndrome (OHSS) may occur in patients whose ovaries excessively react to the drugs. There may occur abdominal swelling, pain, dyspnea. In the event of heavy progress of this situation, increase in these complaints and possibility of life-threatening situation may be possible.Is the tube baby treatment the last cure?
Tube baby treatment is not always the last cure. It should be sometimes tried as the first cure. It can be preferred by foreseeing that the ovary reserve will decrease in time and the possibility of getting pregnant with tube baby for the patient will decrease by trying other treatment methods without beginning to tube baby treatment in young couples who cannot have a child. Or because continuing to try other treatment methods in couples who have tried to get pregnant but become unsuccessful may continue to cause physical and spiritual damage, tube baby treatment can be preferred.
What is the chance of success in tube baby process?
The success depends on the woman’s age and embryo quality. The pregnancy rates under the age of 30 are around 50% and it reduces to 15-20% after the age of 40.
What are the factors which affect the success at most during the tube baby treatment?
The age of woman whom tube baby will be applied on, availability of embryo quality and uterus quality for embryo clinging, sperm quality and infertility duration are the factors which affect the success at most.
In which situations can the treatment be accepted as unsuccessful and cancelled?
The reaction of the ovaries may be insufficient and your treatment may be cancelled before the egg collection. Although there is follicule developed within the ovaries, there may not be any egg within it. This situation has two main reasons. There may not be any egg within the follicules (empty follicule syndrome). This situation is seen in less than 1% of the patients.
In the other situation, follicules may crack before the egg collection. This situation is seen in 2-5% of the patients depending on the stimulation protocol applied. The eggs collected will be empty in this situation.
The eggs may not be fertilized. This situation is really rare in the era of microinjection. However, fertilization may not occur in 2-5% of the patients depending on the abnormal eggs. The eggs fertilized may not divide. This situation is also rare and generally depends on the egg disorder. In azoospermic man, no sperm may be found with surgery. In such a situation, the treatment is cancelled before the egg collection. There may not be found any sperm in the cases of PGD. In such a situation, embryo transfer is not appliedWhat are the factors which affect the success negatively in tube baby treatment?
The existence of problems such as adherence, myoma or polype which will prevent the embryos from clinging within the womb, blocked tubes and water in them affect the success negatively in tube baby.
How long should we take a break after a successful trial?
The duration necessary for a second treatment changes according to the reason of treatment applied and age of expectant mother. In young expectant mothers, we should wait for two times at least. However, in older ages, it may be possible to reduce this duration.
How many times can tube baby be tried?
As long as the follicule development in the ovaries continues and there is physical and spiritual power of the couple, tube baby application can be continued. There is no upper limit for this.
Does tube baby treatment have side effects for long periods?
Because tube baby treatment is applied on the infertile couples and the possibility of breast and ovary cancer in infertile women is more, whether the increasing breast and ovary cancer are a result of treatment or a present risk is researched. Routine examinations should be applied and mammographies of older women should definitely be made.
What can be done in repeating abortions or tube baby failures?
The abortions for 2 times or more before the twentieth pregnancy week and the weight of the baby reaches 500 g are called as repeating abortion. The possibility of abortion again is 25% after the first one, 30% after the second and 40% after the third. The treatment of repeating abortion should be applied according to the abortion reason. In genetic problems, PDG application increases the success. In the problems based on the immune system, paternal lymphocyte immunization may help obtain pregnancy. Pathologies within the uterine cavity can be treated with a system called as hysteroscopy in which the womb inside is entered with a camera and a treatment is also provided; structural or acquired pathologies within the abdomen and tubes can be treated with a method called as laparoscopy and known as closed surgery and so that pregnancy can be tried again. If there are systemic diseases such as possible thyroid, diabetes, autoimmune diseases, anemia, excess weight and deficiency, they should be treated.
How important is the tube baby laboratory in the treatment?
The quality of tube baby laboratory established, devices and materials used affects the results. Experience of embryologists and clinicians and their cooperation, preparation of the patients clinically and resulting the laboratory studies in healthy and the best way are connected with the success of the treatment.
What should be regarded while choosing tube baby center?
Firstly, it should be a center certified by the Ministry of Health. After the transfer, the pregnancy rates can be asked. Tube baby is not the work of only one doctor, but a team. The experience of gynecologist, urologist (about TESET) and embryologist who will follow you should be investigated. If there is a need of pregenetic diagnosis method, whether there are opportunities such as having knowledge, skilld and equipment and application of freezing remaining embryos and application of microtese method if there is not any sperm in the semen can be asked. Apart from this, successful centers should be places in which couples can stay away from stress and feel comfortable.
How is the success of tube baby center measured and how does it change?
The clearest evidence of the success of a tube baby center is to have a high rate of bringing an alive and healthy baby to house. The second important statistical rate is the pregnancy rate after the transfer.
What should be regarded in the advertisements under the name of innovations in the tube baby treatment?
Scientific studies made in the methods presented as innovation should be investigated.
What is embryoscope?
Embryoscope is a device that increases the pregnancy chance in the tube baby treatment.
What are the characteristics of embryoscope?
Control of all embryos automatically in every 20 minutes.
Developed microscope system that does not miss any changes.
Prevention of contact with the white light along the embryo development.
Exact determination of division times. Opportunity of observation for 24 hours day and night.Can PGD be used in prevention of transmission of genetic diseases?
Yes, a disease passing from generation to generation can be prevented by distinguishing of some of the genetic diseases on embryos
What does HLA compatible baby mean?
It is bearing a sibling who can give marrow to his/her sibling in treatments such as thalassemia which requires bone marrow treatment.
What is PGD Fish?
Genetic research is made on 13, 18, 21, X and Y chromosomes with the PGD Fish.
What is the 24 Sure technique?
Unlike PGD Fish, genetic research is made on all 23 chromosomes.
Do embryos get damaged in the PGD process?
When biopsy process is applied by expert embryologists in an experience clinic, embryos absolutely do not get damaged.
What is the difference between the PGD Fish and 24 sure?
While the PGD Fish can detect the 70-75% of the present chromosomal disorders, this rate is close to 100% with the 24 sure.