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A new device in solution of the womb problems: Pregnancy vaccine
As everybody knows, pregnancy cannot be achieved in some patients who have tube baby treatment despite 2 and more trials. When looked into the medical literature, we generally see problems in egg and sperm development, stopping of embryo its development before clinging to the womb and/or achievement of low quality embryos, chromosomal/genetic disorders, immunological problems, factors of womb structure or internal membrane as the reasons of failure.
Various treatment opportunities (Selection of sperms in high growing (IMSI), endometrial coculture, preimlantation genetic diagnosis etc) are provided for the couples who have experienced / experience repeating tube baby failure because of these problems. In addition, good embryo quality is provided in a certain group of patients and embryo transfer is made in proper conditions (although the treatment options written above are applied), and usage of the technique called as pregnancy vaccine with the aim of recruitment of womb environment for embryo if pregnancy does not occur has become a current issue.
The scientific bases of the technique are actually used in routine applications by some gynecologists and infertility specialists in clinic practice for a certain time. In the approach of pregnancy vaccine, the increase in pregnancy rate is provided with the combination of two different application in the same treatment cycle. During tube baby application, small scratches are created in the womb membrane before or after the egg collection process and so bleeding increase is provided in this part. In addition, the cells which are called as monocyte and have important functions for immune system are distinguished in the blood taken from the patient and grown within a special media in laboratory environment and monocytes are enabled to produce different growing factors and hormones within this media. Achieving a better micro environment for the embryo is aimed by washing the womb with this media obtained before the embryo transfer. In fact, some companies today announce that they get increase in the embryo quality and/or pregnancy rates by adding some of these hormones into commercial embryo culture liquids they produce.
It will be determined more accurately that how effective the pregnancy vaccine, a method that has been tried in only a few centers and proved that it is effective, is when compared to other methods with the controlled and central studies which will be made in near future.